Microorganisms in extreme environments represent a promising source of novel metabolites, yet their global diversity and biosynthetic potential remain underexplored. Here, we reconstruct 78,213 ...

We are living in an era where biology has become synonymous with big data due to the ever-increasing amount of data being generated by technologies such as next-generation sequencing. Bioinformatics ...

In bioinformatics, one of the most important problems is comparing biological sequences such as DNA, RNA, or proteins. Since these sequences are often very long, manual comparison is practically ...

This package contains Python bindings for parasail. Parasail is a SIMD C (C99) library containing implementations of the Smith-Waterman (local), Needleman-Wunsch (global), and semi-global pairwise ...

UCL Eastman’s Ian Needleman, Professor of Periodontology, has won UCL’s Public Engagement Institutional Leadership Award for 2017. This important award reflects Ian’s leadership and industry in many ...

Extracellular matrices direct the formation of mineral constituents into self-assembled mineralized tissues. We investigate the protein and mineral constituents to better understand the underlying ...

Abstract: The Needleman-Wunsch algorithm is a global sequence alignment algorithm that has traditionally been used for DNA, RNA, and protein sequencing. Image comparison is used in multiple ...

Efficient implementations of Needleman-Wunsch and other sequence alignment algorithms written in Rust with Python bindings via PyO3. Less-wrong single-file Numba-accelerated Python implementation of ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. While the acquisition of cryo-electron microscopy (cryo-EM) at near-atomic resolution ...