Nature

Public platform with 39,472 exome control samples enables association studies without genotype sharing

Acquiring a sufficiently powered cohort of control samples matched to a case sample can be time-consuming or, in some cases, impossible. Accordingly, an ability to leverage genetic data from control ...
Nature

Exome sequencing analysis of Japanese autism spectrum disorder case-control sample supports an increased burden of synaptic function-related genes

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interactions and repetitive behaviors manifesting in early childhood [1]. Little is known regarding ...
BMJ

Motivation and methods for a first population-based case-control study of traumatic brain injury (TBI) and chronic traumatic encephalopathy (CTE)

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...
Medscape

INTERHEART: A Global Case-Control Study of Risk Factors for Acute Myocardial Infarction

Whereas cardiovascular disease-related mortality has declined in most developed countries, its known prevalence is increasing worldwide, although few data on the causes of heart disease in the ...