Advanced therapeutics, such as cell engineering, gene therapy, and immune engineering, comprise the next generation of life-enhancing and curative interventions. As new therapies gain approval, the ...

Adoptive therapies based on CAR/TCR T cells—that is, T cells with an engineered chimeric antigen receptor (CAR) or a T-cell receptor (TCR)—have shown promise for a range of cancers, offering hope to ...

Three-dimensional (3D) cell culture systems better simulate the in vivo microenvironment by promoting intercellular interactions and functional expression, which are crucial for tissue engineering and ...

UBC research associate Dr. Ross Jones in the lab where they are working to develop cell-based therapies from stem cells. Credit: Phillip Chin. For the first time, researchers at the University of ...

CARs combine the MHC-independent ability of antibodies to bind either membrane-bound or soluble antigens with the signal-transducing properties of the T cell receptor (TCR) machinery. The binding ...

Cell therapy is an advanced biomedical approach that utilizes living cells as therapeutic agents to treat disease or repair tissue. 4 Scientists isolate cells from a patient or a healthy donor and ...